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What impact do antacids have on nutrient absorption?

  1. They enhance B12 absorption

  2. They increase stomach acidity

  3. They decrease nutrient absorption due to lower acidity

  4. They have no effect on nutrient absorption

The correct answer is: They decrease nutrient absorption due to lower acidity

Antacids are compounds that neutralize stomach acid, leading to a decrease in the acidity of the stomach's contents. Since many nutrients require a certain level of acidity for optimal absorption, the use of antacids can negatively impact the absorption of specific vitamins and minerals. For example, vitamin B12 absorption is particularly affected because it requires an acidic environment for its release from food and subsequent absorption in the intestines. Additionally, other nutrients such as calcium, iron, and magnesium may also face absorption challenges due to the decreased acidity caused by antacids. Therefore, the correct response recognizes that the reduction in stomach acidity from antacid use can indeed lead to a decrease in the absorption of several key nutrients, making it a significant consideration in clinical nutrition and supplement recommendations.